Rejected
at 12:06 a.m. Nov, 01, 2023 ]
by
dollajas
Author:
seongwj11
Type of change:
New Tags
Rationale for change
Updates in Sketchypharm
Rejection reason
Discussed with user, need to approach these updates through the formal channels
No changes in fields
Text
Cyclosporine and tacrolimus are {{c2::calcineurin}} inhibitors that block T cell activation by preventing {{c1::IL-2}} transcription
Extra
Calcineurin has phosphatase activity, which dephosphorylates the NFAT transcription factor, activating it and causing it to transcribe genes for IL-2
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