Seizures neither have to be synchronous firing of neurons nor have to occur in the awake brain (actually, many seizures occur in sleep in certain types of seizure disorders). There's lots of debate as to what constitutes a seizure, but the propsed definition is a simple one most can agree on. Source, my PhD dissertation :) https://repository.upenn.edu/edissertations/4801/ Previous cloze is too long (>4ish words), so also making the cloze in the proposed definition the most salient part. Also, it could be considered this card is too basic and should be deleted, but so many times I've seen in epilepsy clinic a patient asks "what is a seizure", or "what is epilepsy", so probably good to be able to spew out "it's just irregular electrical activity in the brain" to the patient since it's a simple thing for us to memorize