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- Type I cryoglobulinemia: an immune-mediated disorder characterized by the deposition of monoclonal immunoglobulins (IgG and IgM) within blood vessels. Most commonly associated with protein-secreting monoclonal gammopathies, including monoclonal gammopathy of undetermined significance, Waldenstrom macroglobulinemia, and multiple myeloma
- Type II (mixed) cryoglobulins are monoclonal IgM and polyclonal IgG antibodies
- Type III (mixed) cryoglobulins are polyclonal IgM and polyclonal IgG antibodies
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