Accepted
at 1:24 p.m. Dec, 17, 2023
by
Ahmed7
Author:
allenlistar
Co-authors:
Ahmed7
Type of change:
Updated content
Rationale for change
Little confused here: graphic shows that ATM is primarily involved in homologous recombination, whereas NHEJ involves Ku70/80 as primary sensors of DNA damage. The way the graphic is drawn - ATM doesn't even seem to be involved in Artemis recruitment in NHEJ.
There is literature suggesting that ATM is in NHEJ, but could the graphic be updated then?
Before
After
Extra
Extra
Extra
Extra
Text
In nonhomologous end joining (NHEJ), dsDNA breaks are recognized by {{c2::ATM}}, recruiting the MRN complex which then recruits the {{c1::Artemis}} protein and various others to help repair the damage
Lecture Notes
Empty field
Missed Questions
Empty field
Pathoma
Empty field
Boards and Beyond
Empty field
First Aid
Sketchy



Watch DNA Repair Mechanisms



Watch DNA Repair Mechanisms
Sketchy 2
Empty field
Sketchy Extra
Empty field
Picmonic
Empty field
Pixorize
Empty field
Physeo
Empty field
Bootcamp
Watch associated Bootcamp video - DNA Mutations, Damage, and Repair: Double Stranded Repair
OME
Additional Resources



One by one
Empty field
