Rejected at 10:41 p.m. Oct, 31, 2023 ] by dollajas
Author: thomas.holmes
Related Note: 1572623455160 1
Rationale for change

Endothelin-1 is a vasoconstrictor, not vasodilator. Additionally, the mechanism appears to be wrong (according to Amboss). Amboss lists the mechanism as occuring due to reduced metabolism of endotoxins from GI bacteria, stimulating production of cytokines and NO (vasodilator). See Hepatopulmonary Syndrome in Amboss for full mechanism.

Rejection reason

endothelin 1 is still increased according to amboss

Text Text
Extra
If vasodilation is severe enough, the lungs can lose their ability to effectively transfer oxygen to the body
Currently, the only known cure for HPS is a liver transplant
Lecture Notes
Empty field
Missed Questions
Empty field
Pathoma
Empty field
Boards and Beyond
Empty field
First Aid
Empty field
Sketchy
* NO and endothelin-1 (ET-1) cause pulmonary vasodilatation



Watch Cirrhosis Pathogenesis & Clinical Manifestations
Sketchy 2
Empty field
Sketchy Extra
Empty field
Picmonic
Empty field
Pixorize
Empty field
Physeo
Empty field
Bootcamp
Watch associated Bootcamp video - Hepatic Pathology : Cirrhosis
OME

Additional Resources
Empty field
One by one
Empty field
#AK_Step1_v12::^Systems::GI::JBadds #AK_Step1_v12::#Bootcamp::Gastroenterology::06_Hepatic_Pathology::05_Cirrhosis #AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_GI::GI_Pathology #AK_Step1_v12::#FirstAid::09_Gastrointestinal::04_Pathology::31_Cirrhosis_and_portal_hypertension::*Hepatopulmonary_Syndrome #AK_Step1_v12::#SketchyPath::06_Hepatobiliary::02_Liver_Disease::01_Cirrhosis_-_Pathogenesis_&_Clinical_Manifestations #AK_Step1_v12::^Systems::GI::pathology #AK_Step1_v12::$AnKingAdds::USMLE_Rx #AK_Step1_v12::!FLAG_THESE_CARDS::SketchyPathAdds #AK_Step1_v12::#OME_banner #AK_Step1_v12::^Other::^HighYield::4-LowerYield #AK_Step1_v12::^Other::^EXPN::JBadd !AK_UpdateTags::Step1decks::Zanki-Step-Decks::Zanki-GI::GI-Pathology #PANCE::EOR::Family_med #AK_Step1_v12::#NBME::25 #AK_Step1_v12::$AnKingUpdates::$Errata::v09