Rejected at 4:12 a.m. May, 02, 2024 ] by herstein.jacob
Author: mbmaa
Co-authors: herstein.jacob
Related Note: 1487642744886
Rationale for change

made the same suggestion twice by mistake

"Phagocytes of patients with CGD can utilize H2O2 generated by invading organisms and convert it to ROS."
FA pg107

I havn't found a source that says CAT -ve bacteria are dealt with specifically by HClO (Hypochlorous acid is written without the -ve sign)

Also note:1487642773652 states that MPO deficiency is associated with increased Candida infections (not CAT -ve bacterial infections)
& has this in its EXTRA field:
"HClO is important for killing off Candida, but H2O2 and other free radicals are sufficient for killing off catalase +ve species
In contrast to chronic mucocutaneous candidiasis, where there is a defect either with Th17 response or AIRE"


I also changed the wording of the sentence in the EXTRA field because it was a bit confusing despite being copied as is from FA pg107
you're probably better at English than me, so change it back if I'm wrong

Rejection reason

Downvotes/see discussion

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#AK_Step1_v12::#Pixorize::02_Immunology::06_Immunodeficiencies::08_Chronic_Granulomatous_Disease_(CGD) #AK_Other::!AK_UpdateTags::AnKing_Image::Aiman::Respiratory_Burst #AK_Step1_v12::#B&B::13_Immunology::02_Clinical_Immunology::03_Immune_Deficiency_Syndromes #AK_Step1_v12::#B&B::04_Biochem::02_Metabolism::05_HMP_Shunt #AK_Step1_v12::#Bootcamp::Microbiology::01_Fundamentals_of_Bacteriology::03_Bacterial_Morphology #AK_Step1_v12::#Physeo::^physeo_image_update #AK_Step1_v12::#Physeo::08_Immunology::01_Immunology::03_Neutrophils #AK_Step1_v12::#Bootcamp::Biochemistry::07_Oxidative_Stress::04_Respiratory_(Oxidative)_Burst:_Clinical_Implications #AK_Other::!AK_UpdateTags::AnKing_Image::!Subjects::Immunology_&_Pathology::Respiratory_Burst #AK_Step1_v12::#B&B::18_Pathology::01_General::03_Free_Radicals #AK_Step1_v12::#OME::PreClinical::Immunology #AK_Step1_v12::#Pathoma::02_Inflammation::01_Acute_Inflammation::3 #AK_Step1_v12::#AMBOSS::ymadRO #AK_Other::#AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Immunology_+_General_Pathology::Pathoma_Chapter_2_(Inflammation) #AK_Step1_v12::#Low/HighYield::2-RelativelyHighYield #AK_Step1_v12::#FirstAid::02_Immunology::03_Immune_Responses::07_Respiratory_burst::*Chronic_Granulomatous_Disease #AK_Step1_v12::#Physeo::08_Immunology::02_Immunodeficiencies::14_Chronic_Granulomatous_Disease_(CGD) #AK_Step1_v12::#B&B::14_Infectious_Disease::01_Basics_of_Microbiology::07_Bacterial_Identification::Extra #AK_Step1_v12::#AMBOSS::QYauKQ #AK_Step1_v12::#AMBOSS::MkaMok