Accepted
at 10:05 a.m. Nov, 24, 2023
by
Ahmed7
Author:
fadiamk
Rationale for change
The best initial treatement for a child who presents with facial flushing, edema, hypotension, wheezing and difficulty breathing after lunch.
UWorld Step 2 QID: 4699
No changes in fields
Text
What is the best treatment to minimize the development of life-threatening complications in patients with anaphylaxis (e.g., hypotension, upper airway edema)?
{{c1::Intramuscular epinephrine 1:1000 (1 mg/mL)::include ROA}}
Extra
- α1 stimulation for vasoconstriction (increases blood pressure and reduces edema)
- β2 stimulation for bronchiole dilation
- Some cases require additional doses of epinephrine for refractory symptoms
- IV epinephrine is indicated for patients with anaphylaxis who do not respond to initial IM epinephrine (IV is associated with a higher risk of cardiovascular arrhythmia)
- Can also use H1/H2 blockers, albuterol, steroids
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