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braviboron/08.21.25-06:40AM
Accepted at: Oct, 03, 2025
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braviboron
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1675118865074
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Rationale for new note
Serotonin
Text
Which neuromuscular signs are characteristic of serotonergic toxidrome?
{{c1::Hyperreflexia, clonus, ocular clonus, myoclonus, shivering, tremor, hypertonia, rigidity}}
{{c1::Hyperreflexia, clonus, ocular clonus, myoclonus, shivering, tremor, hypertonia, rigidity}}
Text
Which <u>neuromuscular signs</u> are characteristic of <b>serotonergic toxidrome</b>?<br><br>{{c1::Hyperreflexia, clonus, ocular clonus, myoclonus, shivering, tremor, hypertonia, rigidity}}
Extra


- Meuromuscular excitation includes hyperreflexia, clonus, ocular clonus, myoclonus, shivering, tremor, hypertonia, rigidity
- Autonomic effects includes hyperthermia, sweating, flushing, mydriasis, tachycardia
- CNS effects include agitation, anxiety, confusion, altered conscious state

Photo credit: Paul Marquis,, via Ortho Eval Pal, used with permission

Video credit: Meegada et al., CC BY 3.0, via Cureus, modified by converting into GIF
Extra
<ul>
<li>Meuromuscular excitation includes hyperreflexia,
clonus, ocular clonus, myoclonus, shivering,
tremor, hypertonia, rigidity</li>
<li>Autonomic effects includes hyperthermia, sweating, flushing, mydriasis, tachycardia</li>
<li>CNS effects include agitation, anxiety, confusion, altered conscious state</li></ul><div><img src="ff0a2c96fa5fe20ecc004c44ef645e4d.webp"><br><div class="figure-citation" style="font-size:10px;"><i>Photo credit: <a href="https://www.youtube.com/watch?v=QocYNeNm3io&ab_channel=OrthoEvalPalwithPaulMarquisPT">Paul Marquis,</a>, via <a href="https://orthoevalpal.com/">Ortho Eval Pal</a>, used with permission</i></div><br><img src="fdc4e2ea88006fcbf7857430558f7a21.webp"><br><div class="figure-citation" style="font-size:10px;"><i>Video credit: <a href="https://www.cureus.com/articles/25146-metoclopramide-induced-serotonin-syndrome#!/">Meegada et al.</a>, <a href="https://creativecommons.org/licenses/by/3.0/deed.en">CC BY 3.0</a>, via Cureus, modified by converting into GIF</i></div></div>
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eTG Complete
eTG Complete
<img src="58fc73d5cd3f5484abc2ceac554c11a5.webp">
Talley & O'Connor
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Talley & O'Connor
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Source
eTG - Serotonergic toxidrome https://app-tg-org-au.ap1.proxy.openathens.net/viewTopic?etgAccess=true&guidelinePage=Toxicology and Toxinology&topicfile=toxidrome-serotonergic&guidelinename=Toxicology and Toxinology§ionId=toc_d1e47#toc_d1e47 Published/Amended August 2020, Accessed 21 August 2025
Source
eTG - Serotonergic toxidrome <a href="https://app-tg-org-au.ap1.proxy.openathens.net/viewTopic?etgAccess=true&guidelinePage=Toxicology%20and%20Toxinology&topicfile=toxidrome-serotonergic&guidelinename=Toxicology%20and%20Toxinology&sectionId=toc_d1e47#toc_d1e47">https://app-tg-org-au.ap1.proxy.openathens.net/viewTopic?etgAccess=true&guidelinePage=Toxicology and Toxinology&topicfile=toxidrome-serotonergic&guidelinename=Toxicology and Toxinology&sectionId=toc_d1e47#toc_d1e47</a> Published/Amended August 2020, Accessed 21 August 2025
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Tags
#Malleus_CM::#eTG_Complete::Toxicology_and_Toxinology::Toxidromes::Serotonergic_toxidrome
#Malleus_CM::#Resources_by_Rotation::Emergency
#Malleus_CM::#Resources_by_Rotation::Psychiatry
#Malleus_CM::#Subjects::Critical_Care::05_Exposure::01_Drug-related_Disorders::Serotonin_Syndrome::06_Clinical_Features