Accepted at 10:47 a.m. Nov, 07, 2023 by Sameem
Author: gpommier
Related Note: 1476583846055
Rationale for change

"What is the clinical manifestation of severe vitamin C deficiency?" is much clearer than "what pathology is associated with vitamin deficiency", where "pathology" can mean many different things.

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These patients can't hydroxylate pro-alpha chains (hydroxylation of proline or lysine requires vitamin C), thus they can't form the triple helix and the nascent collagen is degraded in the cell without being secreted
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
Sketchy
Sketchy 2
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Sketchy Extra
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Picmonic
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Physeo




OME

Additional Resources
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One by one
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#AK_Step2_v12::Original_decks::Zanki_Step_2::Peds::Step_1_Pediatrics #AK_Step1_v12::#AMBOSS::Gu0Bs3 #AK_Step1_v12::#UWorld::COMLEX::24358 #AK_Step1_v12::#Pixorize::01_Biochemistry::01_Vitamins::16_Vitamin_C_(Ascorbic_Acid)_Deficiency_&_Excess #AK_Step1_v12::#UWorld::Step::1247 !AK_UpdateTags::Step1decks::Zanki-Step-Decks::Zanki-Biochemistry::Vitamins #AK_Step1_v12::#FirstAid::01_Biochem::05_Nutrition::14_Vitamin_C #AK_Step2_v12::#AMBOSS::bKaHUl #AK_Step1_v12::#FirstAid::01_Biochem::05_Nutrition::14_Vitamin_C::02_Deficiency #AK_Step1_v12::#AMBOSS::bKaHUl #AK_Step1_v12::#AMBOSS::ihaJd4 #AK_Step2_v12::#Resources_by_rotation::Peds::step1_pediatrics_zanki #AK_Step1_v12::#Physeo::^physeo_image_update #AK_Step1_v12::^Other::^EXPN::BGedit #AK_Step1_v12::^Other::^FA_Updates::FA2018 #PANCE::EOR::PEDS #PANCE::GI::nutrition #AK_Step1_v12::#B&B::06_Cell_Bio::03_Cellular_Biology::04_Connective_Tissue #AK_Step1_v12::#OME::PreClinical::Biochemistry #AK_Step1_v12::#Physeo::05_Biochem::05_Metabolism::28_Nutrition #AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Biochemistry::Vitamins #AK_Step1_v12::^Other::^HighYield::1-HighYield #AK_Step1_v12::^Systems::Biochem::vitamins #AK_Step1_v12::#Bootcamp::Gastroenterology::04_Physiology::08_Vitamins #AK_Step1_v12::#Physeo::05_Biochem::05_Metabolism::37_Vitamin_C_-_Nutrition #AK_Step1_v12::#Bootcamp::Biochemistry::12_Vitamins::09_Vitamin_C #AK_Step1_v12::#SketchyBiochem::04_Vitamins/Minerals::01_Water_Soluble::09_Vitamin_C #AK_Step2_v12::!Shelf::Peds::no_dupes