Accepted
at 12:35 p.m. Nov, 06, 2023
by
Ahmed7
Author:
Ahmed7
Type of change:
Updated content
Rationale for change
more accurate. ranolazine inhibits the "late inward Na+ current". saying the late phase of the Na current is not entirely accurate
AMBOSS: "Inhibition of late inward sodium channels on cardiac myocytes → reduced calcium influx via sodium-calcium channel pump → reduced wall stress and MVO2 [31]"
Source: AMBOSS - https://next.amboss.com/us/article/DS01bf?utm_source=navbar&utm_medium=anki&utm_campaign=anki&utm_term=ranolazine&guid=jp%257D%253AkGI%253ARh&aid=2e67bfb7-e0f1-41ee-8b53-30b1e0d5cb27&uid=VbbTGsH6a#Z22b473b7dfb6afb1977c3c80d39a16fb
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Reduces diastolic wall tension and oxygen consumption.
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