Accepted
at 10:25 p.m. Oct, 28, 2023
by
Ahmed7
Type of change:
Updated content
Rationale for change
Original was kind of confusing having "not endochondral" as a clue given the failure of endochronal ossification leads to the impaired longitudinal growth.
AMBOSS:
Defective FGFR3 → continuous receptor stimulation by FGF → inhibited chondrocyte proliferation → ↓ endochondral ossification → impaired longitudinal bone growth
Source: AMBOSS - https://next.amboss.com/us/article/wH0hsh?q=achondroplasia#y0WdiP0
Before
After
Text
Text
Text
Text