Accepted
at 4:13 a.m. Nov, 01, 2023
by
rockroovy
Author:
mason.allen
Type of change:
Content error
Rationale for change
above diaphragm, not below
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After
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MOA: Clindamycin
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Inhibits 50s ribosome ⇒ Blocks translocation
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Is Clindamycin bacteriostatic or bacteriocidal?
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Bacteriostatic
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What is the spectrum of activity of Clindamycin?
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(1) Gram (+)
(2) Anaerobes
(Occasionally used for plasmodium)
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What type of Strep. pyogenes infections is Clindamycin indicated for?
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Soft tissue
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Does Clindamycin or Azithromycin have activity against MRSA?
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Clindamycin
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What type of anaerobic infection is Clindamycin particularly effective against?
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Lung abscesses
(Accumulates in MΦs)
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What antibiotic is indicated in treatment of pneumonia due to Bacteroides fragilis?
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Clindamycin
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Clostridium perfringens ⇒ Gas gangrene
(Clindamycin above diaphragm, metronidazole below)
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Treatment: Polymicrobial infections of female genital tract
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Clindamycin + Gentimicin
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Which protein synthesis inhibitor is used for Gardnerella vaginalis?
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Clindamycin
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Adverse Effect: Clindamycin
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Diarrhea
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What antibiotic is most frequently implicated in causing pseudomambranous colitis?
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Clindamycin
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2.3 - Clindamycin