Accepted
at 4:01 a.m. Nov, 01, 2023
by
TheAnKing
Author:
abal
Type of change:
Updated content
Rationale for change
does not need cloze deletion for this portion
Before
After
Text
Text
Text
Text
Extra
1: Aromatic end: lipophilic portion, affects potency (more lipid soluble → more potent) and duration (more lipid soluble → longer duration because re-lingers longer in tissues)
2: Intermediate chain: linkage portion; either amide or esther
3: Amine end: hydrophilic, binds sodium channel, determines onset of action; more rapid onset when amine group is unprotonated vs. protonated → alkalinization with bicarbonate speeds onset by decreasing proportion of positively charged/protonated amine groups
2: Intermediate chain: linkage portion; either amide or esther
3: Amine end: hydrophilic, binds sodium channel, determines onset of action; more rapid onset when amine group is unprotonated vs. protonated → alkalinization with bicarbonate speeds onset by decreasing proportion of positively charged/protonated amine groups
Personal Notes
Empty field
Missed Questions
Empty field
DermPath
Empty field
Dermoscopy
Empty field
VisualDx
Empty field
DermNet
Empty field
Full Spectrum of Dermatology
Empty field
Dermnemonics
Empty field
Dermatographix
Empty field
Textbook
Empty field
Additional Resources
Empty field
One by one
Empty field