Rejected
at 3:54 a.m. Nov, 01, 2023 ]
by
Ahmed7
Author:
Huzaifa
Type of change:
Updated content
Rationale for change
Amboss lists both as first line
Source: AMBOSS - https://next.amboss.com/us/review/7r2-4iQ9V/4
Rejection reason
comments
Current
Suggested
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- The first-line treatment option for patients with Nelson syndrome
- Pituitary radiation therapy may be needed if the tumor is not fully resectable
1) Indications include primary Cushing syndrome due to bilateral adrenal disease or severe secondary Cushing syndrome refractory to treatment
2) Bilateral adrenalectomy causes sudden drop in cortisol
3) Loss of negative feedback from cortisol
4) Increased corticotropin-releasing hormone (CRH) production
5) Enlargement of preexisting but undetected pituitary adenoma
6) Symptoms manifest (e.g., hyperpigmentation, headaches, & bitemporal hemianopsia)
- Pituitary radiation therapy may be needed if the tumor is not fully resectable
- Nelson syndrome is a complication that can occur following bilateral adrenalectomy for Cushing syndrome
- This card previously only said "radiotherapy of the pituitary," but it was updated to include transsphenoidal resection as an option, according to AMBOSS and UpToDate (June 2025)
1) Indications include primary Cushing syndrome due to bilateral adrenal disease or severe secondary Cushing syndrome refractory to treatment
2) Bilateral adrenalectomy causes sudden drop in cortisol
3) Loss of negative feedback from cortisol
4) Increased corticotropin-releasing hormone (CRH) production
5) Enlargement of preexisting but undetected pituitary adenoma
6) Symptoms manifest (e.g., hyperpigmentation, headaches, & bitemporal hemianopsia)
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
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Sketchy
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Sketchy 2
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Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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Bootcamp
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OME
Additional Resources
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One by one
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