Rejected at 8:06 p.m. Dec, 27, 2023 ] by Ahmed7
Author: Huzaifa
Related Note: 1535830169322
Rationale for change

Amboss lists serum cortisol as option too

Source: AMBOSS - https://next.amboss.com/us/article/fg0ku2?utm_source=anki&utm_medium=anki&utm_campaign=anki&utm_term=cushing%2Bsyndrome&guid=M%2526a%253AlgJ%25210%257B&aid=f9e4af89-e589-4805-944e-c3b35ebbd8d6&uid=2AnfTQD5a#Zd6f2c97ce2ff59be2266a924adc28d81

Rejection reason

Please resubmit with an acceptable rationale. Please review suggestion guidelines, specifically rule #2: http://www.theanking.com/decks/step/suggestions

Text Text
Extra
If ≥ 2 of these tests are positive, hypercortisolism is confirmed → measure ACTH next

1. Average of cortisol over 24 hours. A level more than three times the upper limit of normal indicates hypercortisolism
2. Normal saliva = ↓ cortisol at night
3. Exogenous cortisol should negatively inhibit cortisol (is the most sensitive test), so cortisol should be low; however, adenomas/tumors do not follow the HPA axis and continue to secrete cortisol

Image licensed by Physeo and used with permission.


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