Accepted
at 3:47 a.m. Nov, 01, 2023
by
Ahmed7
Author:
Ahmed7
Type of change:
Other
Rationale for change
formatting, kept hemolytic in cloze as well since thats what H is for
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- Destroyed platelets release TXA2 / ADP causing thrombocytopenia (mucosal bleeding, petechiae, ecchymoses)

- Hemosiderinuria is seen days after hemolysis, hemoglobinuria can lead to renal failure
- Predominantly intravascular, but can be extravascular (C3 fragments can act as opsonin)
- Venous thrombosis appears in unusual locations (portal, mesenteric, cerebral veins)
PNH urine (left):

Photo credit: Nakamura et al., CC BY 2.0, via BMC Journal of Medical Case Reports
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid


Sketchy 2
P:

N:

H:

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Watch Intravascular Hemolytic Anemia: Non-MAHA DDx





Watch Upper Abdominal Pain DDx



Watch Approach to Hematuria

N:

H:

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Watch Intravascular Hemolytic Anemia: Non-MAHA DDx





Watch Upper Abdominal Pain DDx



Watch Approach to Hematuria
Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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Bootcamp
Watch associated Bootcamp video - Normocytic Anemia: Paroxysmal Nocturnal Hemoglobinuria
Watch associated Bootcamp video - Complement Disorders
Watch associated Bootcamp video - Complement Disorders
OME
Additional Resources
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