Created at 2:13 a.m. Aug, 28, 2026
Author:
soplov17
Type of change:
Updated content
Rationale for change
Peroxisomes are not directly responsible for the synthesis of steroid hormones. From my understanding, they synthesize cholesterol which is an important precursor but not actually the hormone itself.
https://pubmed.ncbi.nlm.nih.gov/9142695/
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Fibrates (gemfibrozil, bezafibrate, fenofibrate) activate PPAR-α to promote peroxisome synthesis of HDL / activity of LPL / decrease VLDL production
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