Accepted at 9:22 p.m. Oct, 31, 2023 by dollajas
Author: claspbone
Related Note: 1556395773720
Rationale for change

Serum sickness (SS) is caused by foreign proteins in antivenom, antitoxin, or monoclonal antibodies. Serum sickness-like reactions (SSLR) are caused by medications like penicillin and TMP-SMX. SS also has high immune complex titers and extensive complement activation, whereas SSLR does not or only minimally.

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- Unlike true serum sickness (type III HSR with immune complex deposition), thought to be caused by hapten-mediated cytotoxicity

- Symptoms resolve completely upon cessation of offending agent
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
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Sketchy


Watch Monoclonal Antibody Therapy
Sketchy 2
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Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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Bootcamp
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OME

Additional Resources
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Changed Tags
#AK_Step2_v12::#UWorld::20700 #AK_Step2_v12::#UWorld::20699
#AK_Step2_v12::#Resources_by_rotation::IM::ome::derm::hypersensitivity #AK_Step2_v12::!Shelf::#Cards_AnKing_Did::3peds #AK_Step2_v12::#Resources_by_rotation::Peds::uworld::ent_allergy_immunology::ent_allergy_immunology_dorian #AK_Step2_v12::Original_decks::Dorian::peds::uw::ent_allergy_immuno #AK_Step2_v12::#Subjects::Immunology_&_Pathology::02_Immunology::Hypersensitivity::Serum_Sickness !AK_UpdateTags::^temporary::ImageFix::Table #AK_Step2_v12::!Shelf::Peds::no_dupes::only_step2 #AK_Step2_v12::#OME::Clinical::01_Medicine::09_Dermatology::04_Hypersensitivity #AK_Step2_v12::#OME::01_Medicine::09_Dermatology::04_Hypersensitivity #AK_Step2_v12::Original_decks::Dorian::im::ome::derm::hypersensitivity #AK_Step2_v12::#AMBOSS #AK_Step2_v12::!Shelf::Peds::no_dupes #AK_Original_Decks::Step_2::Cheesy_Dorian_(M3) #AK_Step2_v12::#UWorld::COMLEX::104837 !AK_UpdateTags::Step2decks::Cheesy-Dorian-(M3)::Pediatrics::3-UWorld::4 #AK_Step2_v12::#UWorld::Step::20699 #AK_Step2_v12::#UWorld::Step::4584 #AK_Step2_v12::#UWorld::COMLEX::101367 #AK_Step2_v12::#AMBOSS::L70wmh