Accepted
at 1:40 p.m. May, 28, 2026
by
Ahmed7
Author:
schwenjd
Type of change:
Updated content
Rationale for change
Per AMBOSS:
Multivitamin preparations invariably include polyvalent cations such as magnesium, calcium, and iron. These cations form complexes with fluoroquinolone antibiotics, severely hampering intestinal absorption of the antibiotic. Strategies to avoid this include intravenous administration of the antibiotic or avoiding oral coadministration (e.g., giving the fluoroquinolone 2 hours before the vitamin or 6 hours after).
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Which antibiotics bind divalent ions (Fe2+, Ca2+, and Mg2+) resulting in chelation?
{{c1::Tetracyclines, fluoroquinolones::2}}
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