Created at 5:36 p.m. Apr, 28, 2026
Author:
mohannadkh10
Type of change:
Content error
Rationale for change
It's contraindicated in the first trimester as it increases the risk of abortion. PDA issues are seen in the second and third trimesters.
https://next.amboss.com/us/article/BN0zWg?q=nsaid%20in%20pregnancy#Z25935fa84695889c0617090889f79360
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- Especially with indomethacin and ibuprofen
- AMBOSS states it is contraindicated in 2nd trimester as well
- Can cause other complications as well (e.g., spontaneous abortion, inhibition of uterine contractility, oligohydramnios, renal dysfunction)
- AMBOSS states it is contraindicated in 2nd trimester as well
- Can cause other complications as well (e.g., spontaneous abortion, inhibition of uterine contractility, oligohydramnios, renal dysfunction)
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