Accepted
at 10:40 p.m. May, 31, 2026
by
Brian_BH
Author:
erfanz18
Type of change:
Content error
Rationale for change
Please update this, it's incorrect and very misleading. Positive selection is about keeping T cells that can recognize self-MHC, not any antigen presentation, and negative selection deletes T cells that bind too strongly to self-antigen on self-MHC, whereas cells that fail to recognize MHC die by neglect rather than by negative selection.
Sources : https://www.khanacademy.org/test-prep/mcat/organ-systems/the-immune-system/a/adaptive-immunity?utm_source=chatgpt.com
https://openstax.org/books/anatomy-and-physiology-2e/pages/21-3-the-adaptive-immune-response-t-lymphocytes-and-their-functional-types
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Maturation of T-cells is facilitated by thymosin and occurs in thymus.

Khan Academy Link
A T-cell that is able to moderately bind to self-MHC and does not strongly bind to self-antigen will survive selection.
Maturation of T-cells is facilitated by thymosin and occurs in thymus.

Khan Academy Link
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