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Thoracic Imaging - Lung cancer

The Fleischner Society pulmonary nodule follow-up recommendations:

SUBSOLID NODULES

Multiple subsolid nodules <6 mm (<100 mm3)
  • {{c1::CT at 3-6 months, then if stable consider CT at 2 and 4 years in high-risk patients::f/u?}}
Multiple subsolid nodules ≥6 mm (>100 mm3)
  • {{c2::CT at 3-6 months, then subsequent management based on the most suspicious nodule(s)::f/u?}}
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<i>Thoracic Imaging - Lung cancer<br></i><br>The&nbsp;<strong>Fleischner Society pulmonary nodule follow-up recommendations:<br></strong><br>SUBSOLID NODULES<br><br><div>Multiple subsolid nodules &lt;6 mm&nbsp;<strong>(</strong>&lt;100 mm<sup>3</sup>)<ul><li><div>{{c1::CT at 3-6 months, then if stable consider CT at 2 and 4 years in high-risk patients::f/u?}}</div></li></ul>Multiple subsolid nodules ≥6 mm (&gt;100 mm<sup>3</sup>)<ul><li><div>{{c2::CT at 3-6 months, then subsequent management based on the most suspicious nodule(s)::f/u?}}</div></li></ul></div>
Extra

The Fleischner Society pulmonary nodule recommendations pertain to the follow-up and management of indeterminate pulmonary nodules detected incidentally on CT and are published by the Fleischner Society. The guideline does not apply to lung cancer screening, patients younger than 35 years, or patients with a history of primary cancer or immunosuppression.
NB: This article reflects the 2017 revision 4, which supersedes prior versions published in 2005 and 2013 2.

Solid nodules
Single
Single solid nodule <6 mm (<100 mm3)
  • low-risk patients: no routine follow-up required
  • high-risk patients: optional CT at 12 months (particularly with suspicious nodule morphology and/or upper lobe location; see "risk assessment" below)
Solitary solid nodule 6-8 mm (100-250 mm3)
  • low-risk patients: CT at 6-12 months, then consider CT at 18-24 months
  • high-risk patients: CT at 6-12 months, then CT at 18-24 months
Solitary solid nodule >8 mm (>250 mm3)
  • low-risk and high-risk patients: consider CT at 3 months, PET-CT, or tissue sampling
Multiple

Multiple solid nodules <6 mm (<100 mm3)
  • low-risk patients: no routine follow-up required
  • high-risk patients: optional CT at 12 months
Multiple solid nodules >6 mm (>100 mm3)
  • low-risk patients: CT at 3-6 months, then consider CT at 18-24 months
  • high-risk patients: CT at 3-6 months, then CT at 18-24 months
When multiple nodules are present, the most suspicious nodule should guide further individualized management.
Subsolid nodules
Single
Single ground glass nodule <6 mm (<100 mm3)
  • no routine follow-up required
Single ground glass nodule ≥6 mm (>100 mm3)
  • CT at 6-12 months, then if persistent, CT every 2 years until 5 years
Single part-solid nodule ≥6 mm (>100 mm3)
  • CT at 3-6 months, then if persistent and solid component remains <6 mm, annual CT until 5 years
Multiple
Multiple subsolid nodules <6 mm (<100 mm3)
  • CT at 3-6 months, then if stable consider CT at 2 and 4 years in high-risk patients
Multiple subsolid nodules ≥6 mm (>100 mm3)
  • CT at 3-6 months, then subsequent management based on the most suspicious nodule(s)
Extra
<div> <div> <div><div><i>Source: Radiopedia&nbsp;<a href="https://radiopaedia.org/articles/fleischner-society-pulmonary-nodule-recommendations-1?lang=us">Fleischner Society pulmonary nodule recommendations | Radiology Reference Article | Radiopaedia.org</a></i></div><br><div>The&nbsp;<strong>Fleischner Society pulmonary nodule recommendations</strong>&nbsp;pertain to the follow-up and management of indeterminate&nbsp;<a href="https://radiopaedia.org/articles/pulmonary-nodule-1?lang=us">pulmonary nodules</a>&nbsp;detected incidentally on CT and are published by the&nbsp;<a href="https://radiopaedia.org/articles/fleischner-society?lang=us">Fleischner Society</a>. The guideline does not apply to lung cancer screening, patients younger than 35 years, or patients with a history of primary cancer or immunosuppression.</div><div>NB: This article reflects the 2017 revision&nbsp;<sup>4</sup>, which supersedes prior versions published in 2005&nbsp;<sup>1&nbsp;</sup>and 2013&nbsp;<sup>2</sup>.</div><br>Solid nodules</div><div>Single</div><div>Single solid nodule &lt;6 mm (&lt;100 mm<sup>3</sup>)<ul><li><div>low-risk patients: no routine follow-up required</div></li><li><div>high-risk patients: optional CT at 12 months (particularly with suspicious nodule morphology and/or upper lobe location; see "risk assessment" below)</div></li></ul>Solitary solid nodule 6-8 mm (100-250 mm<sup>3</sup>)<ul><li><div>low-risk patients: CT at 6-12 months, then consider CT at 18-24 months</div></li><li><div>high-risk patients:&nbsp;CT at 6-12 months, then CT at 18-24 months</div></li></ul>Solitary solid nodule &gt;8 mm (&gt;250 mm<sup>3</sup>)<ul><li><div>low-risk and high-risk patients: consider CT at 3 months,&nbsp;PET-CT, or tissue sampling</div></li></ul>Multiple</div><br><div>Multiple solid nodules &lt;6 mm (&lt;100 mm<sup>3</sup>)<ul><li><div>low-risk patients: no routine follow-up required</div></li><li><div>high-risk patients: optional CT at 12 months</div></li></ul>Multiple solid nodules &gt;6 mm (&gt;100 mm<sup>3</sup>)<ul><li><div>low-risk patients: CT at 3-6 months, then consider CT at 18-24 months</div></li><li><div>high-risk patients: CT at 3-6 months, then CT at 18-24 months</div></li></ul><div>When multiple nodules are present, the most suspicious nodule should guide further individualized management.</div>Subsolid nodules</div><div>Single</div><div>Single ground glass nodule &lt;6 mm (&lt;100 mm<sup>3</sup>)<ul><li><div>no routine follow-up required</div></li></ul>Single ground glass nodule ≥6 mm (&gt;100 mm<sup>3</sup>)<ul><li><div>CT at 6-12 months, then if persistent,&nbsp;CT every 2 years until 5 years</div></li></ul>Single part-solid nodule ≥6 mm (&gt;100 mm<sup>3</sup>)<ul><li><div>CT at 3-6 months, then if persistent and solid component remains &lt;6 mm, annual CT until 5 years</div></li></ul>Multiple</div><div>Multiple subsolid nodules &lt;6 mm&nbsp;<strong>(</strong>&lt;100 mm<sup>3</sup>)<ul><li><div>CT at 3-6 months, then if stable consider CT at 2 and 4 years in high-risk patients</div></li></ul>Multiple subsolid nodules ≥6 mm (&gt;100 mm<sup>3</sup>)<ul><li><div>CT at 3-6 months, then subsequent management based on the most suspicious nodule(s)</div></li></ul></div> </div> </div>
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