Created at 10:11 a.m. Mar, 15, 2026
Author:
birhanbirtane
Type of change:
Content error
Rationale for change
Insulinr receptor is already a pre-formed dimer
Current
Suggested
Text
Text
Text
Text
Extra
1. Insulin binds to the insulin receptor tyrosine kinase
2. Insulin binding induces a conformational change to trigger autophosphorylation by tyrosine kinases
3. IRS binds the insulin receptor and IRS's tyrosine residues are phosphorylated by the activated receptor kinase
4. SH2-domain proteins bind phosphotyrosine residues on IRS

Image licensed by Physeo and used with permission. Purchase full textbook here.
2. Insulin binding induces a conformational change to trigger autophosphorylation by tyrosine kinases
3. IRS binds the insulin receptor and IRS's tyrosine residues are phosphorylated by the activated receptor kinase
4. SH2-domain proteins bind phosphotyrosine residues on IRS

Image licensed by Physeo and used with permission. Purchase full textbook here.
Lecture Notes
Empty field
Missed Questions
Empty field
Pathoma
Empty field
Boards and Beyond
Empty field
First Aid


Sketchy 2
Empty field
Sketchy Extra
Empty field
Picmonic
Empty field
Pixorize


Review Insulin Overview


Review Insulin Overview
Physeo
.jpg)
.jpg)
Bootcamp
Watch associated Bootcamp video - Glycogen: Regulation of Glycogen Metabolism
Watch associated Bootcamp video - Pharmacodynamics: Receptor Physiology
Watch associated Bootcamp video - Pharmacodynamics: Receptor Physiology
OME
Empty field
Additional Resources
One by one
Empty field





