Rejected
at 4:28 p.m. Mar, 14, 2026 ]
by
Rasheed
Author:
motios
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What is the likely diagnosis in a young adult that presents with two days of sore throat, enlarged/erythematous tonsils, lymphadenopathy, and splenomegaly? Many variant forms of lymphocytes are seen on peripheral smear despite a negative heterophile antibody test
{{c1::Infectious mononucleosis}}
Extra
Heterophile antibodies may be falsely negative early in the illness; atypical lymphocytes are suggestive of infectious mononucleosis (found in both EBV and CMV)


Photo credit: Ed Uthman, CC BY 2.0, via Flickr, No machine-readable author provided. NicolasGrandjean assumed (based on copyright claims)., CC BY-SA 3.0, via Wikimedia Commons, איתן פרמן, CC BY-SA 3.0, via Wikimedia Commons; the supplementary image with overlays of the relevant areas was adapted from the image mentioned previously, licensed under CC BY-SA 3.0


Photo credit: Ed Uthman, CC BY 2.0, via Flickr, No machine-readable author provided. NicolasGrandjean assumed (based on copyright claims)., CC BY-SA 3.0, via Wikimedia Commons, איתן פרמן, CC BY-SA 3.0, via Wikimedia Commons; the supplementary image with overlays of the relevant areas was adapted from the image mentioned previously, licensed under CC BY-SA 3.0
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