Rejected
at 8:33 p.m. Oct, 31, 2023 ]
by
Alex
Author:
evanskj
Type of change:
Content error
Rationale for change
RBC antigens in general --> AHTR
Specifically ABO blood groups --> Intravascular subcategory
Non-ABO blood groups (ex: Kell antigen) --> Extravascular subcategory
Rejection reason
comments
Current
Suggested
Text
Text
Text
Text
Extra
- IgM isohemagglutinins formed naturally in response to bacterial flora cause opsonization and complement activation on donor RBCs, leading to hemolysis
- ABO incompatibility is mediated by the complement / IgM, whereas the foreign antigens are opsonized and cleared by the spleen

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Pathoma
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First Aid
FA2020:


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Watch Blood Transfusion Complications






Watch Intravascular Hemolytic Anemia: Non-MAHA DDx




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Watch Blood Transfusion Complications






Watch Intravascular Hemolytic Anemia: Non-MAHA DDx




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Bootcamp
Watch associated Bootcamp video - Transfusion Reactions: Acute Hemolytic Transfusion Reaction
OME
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