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at 4:46 p.m. Jan, 24, 2026
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Ahmed7
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NN vid macrocyctic anemia https://www.youtube.com/watch?v=nUKG5TV4NC4&list=PLTF9h-T1TcJggPpvX_JHtzxfLN_yySpAy&index=3
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What is the diagnosis in a patient with macrocytic anemia, low reticulocyte count, hepatomegaly, and ringed sideroblasts?
{{c1::Myelodysplastic syndrome}}
Extra
- Folate and B12 levels are normal
Figure 1: Blood smear from a person with myelodysplastic syndrome. A hypogranular neutrophil with a pseudo-Pelger-Huet nucleus is shown. There are also abnormally shaped red blood cells, in part related to removal of the spleen
Figure 2: A ring sideroblast visualized by Prussian blue stain
Photo credit: The Armed Forces Institute of Pathology (AFIP), Public domain, via Wikimedia Commons; Paulo Henrique Orlandi Mourao, CC BY-SA 3.0, via Wikimedia Commons
- May present with symptoms of anemia
- Blood smear may show anisocytosis (RBCs of different sizes)
Figure 1: Blood smear from a person with myelodysplastic syndrome. A hypogranular neutrophil with a pseudo-Pelger-Huet nucleus is shown. There are also abnormally shaped red blood cells, in part related to removal of the spleen
Figure 2: A ring sideroblast visualized by Prussian blue stain
Photo credit: The Armed Forces Institute of Pathology (AFIP), Public domain, via Wikimedia Commons; Paulo Henrique Orlandi Mourao, CC BY-SA 3.0, via Wikimedia Commons
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
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Sketchy
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Sketchy 2
Watch Bone Marrow Failure DDx
Watch Anemia Intro: Microcytic Anemia DDx
Watch Macrocytic Anemia DDx
Watch Bone Marrow Failure DDx
Watch Anemia Intro: Microcytic Anemia DDx
Watch Macrocytic Anemia DDx
Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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OME
Additional Resources
May progress to AML (below)
One by one
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