Accepted
at 12:05 a.m. Jan, 24, 2026
by
Ahmed7
Bulk Suggestion
Bulk ID:
Tanner_G/12.30.25-06:17PM
Rationale for change
#AK_Step1_v12::#NinjaNerd::06_Cardiovascular::04_Pharmacology::03_Heparin_(MOA,_Indications,_ADR,_CI)
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Text
How do you initiate anticoagulation in stable DVT patients?
First-line: {{c1::start a DOAC (rivaroxaban or apixaban) immediately (no heparin bridging required)}}
Second-line: {{c1::use heparin (LMWH or UFH) as a bridge to warfarin}}
First-line: {{c1::start a DOAC (rivaroxaban or apixaban) immediately (no heparin bridging required)}}
Second-line: {{c1::use heparin (LMWH or UFH) as a bridge to warfarin}}
Extra
- Continue anticoagulation for 3–6 months; extend based on risk factors
- Long-term LMWH is preferred in pregnancy
- DOACs include factor Xa inhibitors (rivaroxaban, apixaban, edoxaban) and thrombin inhibitors (dabigatran)
- Use UFH initially in patients with renal insufficiency or those at high risk of bleeding (can quickly turn off pump and/or reverse with protamine)
- Real-life pearl: without insurance, DOACs cost about $100+ per month, while warfarin only costs $10 per month. Therefore, most uninsured patients end up on warfarin
- Major updates were made to this card to reflect the current guidelines for anticoagulation in DVT (Sep 2025)
- Long-term LMWH is preferred in pregnancy
- DOACs include factor Xa inhibitors (rivaroxaban, apixaban, edoxaban) and thrombin inhibitors (dabigatran)
- Use UFH initially in patients with renal insufficiency or those at high risk of bleeding (can quickly turn off pump and/or reverse with protamine)
- Real-life pearl: without insurance, DOACs cost about $100+ per month, while warfarin only costs $10 per month. Therefore, most uninsured patients end up on warfarin
- Major updates were made to this card to reflect the current guidelines for anticoagulation in DVT (Sep 2025)
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