Rejected
at 5:06 p.m. Feb, 06, 2026 ]
by
Ahmed7
Author:
shavan16
Type of change:
Content error
Rationale for change
IgM-mediated immune hemolytic anemia usually causes intravascular hemolysis, not extravascular.
Rejection reason
Please resubmit with an acceptable source. Please review suggestion guidelines, specifically rule #1: https://community.ankihub.net/t/anking-step-deck-submission-guidelines/166504
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- IgG → Guarantees extravascular hemolysis
- IgM → Mostly causes extravascular hemolysis
- However, intravascular hemolysis can occur in severe cases through complement activation on RBCs bound by IgM antibodies
- IgG-mediated hemolytic anemia will cause extravascular hemolysis every time however

- IgM → Mostly causes extravascular hemolysis
- However, intravascular hemolysis can occur in severe cases through complement activation on RBCs bound by IgM antibodies
- IgG-mediated hemolytic anemia will cause extravascular hemolysis every time however

Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid


Sketchy



Watch G6PD Deficiency & Autoimmune Hemolytic Anemia (AIHA)
*RBCs with IgM coating are attacked by complement → formation of MAC → hemolysis in blood vessels



Watch G6PD Deficiency & Autoimmune Hemolytic Anemia (AIHA)
Sketchy 2
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Picmonic
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Pixorize
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Physeo
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Bootcamp
Watch associated Bootcamp video - Normocytic Anemia: Autoimmune Hemolytic Anemia
Watch associated Bootcamp video - Normocytic Anemia: Hemolysis
Watch associated Bootcamp video - Normocytic Anemia: Hemolysis
OME
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