Created at 7:53 p.m. Dec, 10, 2025
Author:
ombanister01
Type of change:
Content error
Rationale for change
This card was confusing because terazosin is a selective alpha-1 antagonist if you're looking at it from the perspective of it not being an alpha-2 antagonist as well, but it's important for Step that for BPH, terazosin is nonselective for the subtypes of the alpha-1 receptor, so it's used for pts who have BPH and HTN, but not for normotensive patients. For normotensive patients, you would use tamulsosin because it is selective for alpha-1A/D, which means that it does not cause vasodilation (does not affect alpha-1B like terazosin does). TLDR: tamulsosin is the nonselective alpha-1 antagonist, not terazosin.
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Non-selective for α1A, α1B and α1D → therefore also relaxes vascular smooth muscle and lowers blood pressure
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