Created at 7:21 p.m. Nov, 07, 2025
Author:
adavis98
Type of change:
Updated content
Rationale for change
Unlike many of the inborn errors of metabolism, protein restriction is not recommended (and rather discouraged) as a treatment modality in patients with cirrhosis.
Per Amboss, "Aim for 1.0–1.5 g of protein per kilogram of dry body weight daily; protein restriction is not recommended."
Many current guidelines recommend the opposite of protein restriction: adequate or even increased protein intake to prevent malnutrition and sarcopenia. Malnutrition (especially loss of muscle mass) is common in cirrhosis and is associated with worse outcomes
Source: AMBOSS - https://next.amboss.com/us/article/PS0W-2?q=hyperammonemia%20protein%20cirrhosis#Y7cd8dc35f49ed14190f801970dce0c3d
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Part of the treatment for hyperammonemia is limiting {{c1::protein}} in the diet
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