Accepted at 11:14 a.m. Nov, 06, 2025 by schralp
Author: schralp
Related Note: 1489966869972
Rationale for change

AMBOSS:
"Sirolimus (also known as rapamycin)
Binding to FKBP → inhibition of mTOR kinase → inhibition of the IL-2-mediated cell cycle → ↓ response to IL-2 → ↓ T-cell activation and B-cell differentiation → ↓ IgM, IgG, and IgA production"
Source: AMBOSS - https://next.amboss.com/us/article/qM0Cpg?utm_source=anki&utm_medium=anki&utm_campaign=anki&utm_term=sirolimus&guid=GPk%2523P8cKBM&aid=510e24eb-c971-4fb3-bc87-4b383a06703b&uid=ZLT2aZwrSP#Z5e21c1e69368d1353258ccfad063bbfa

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