Created at 8:25 p.m. Nov, 05, 2025
Author:
Sameem
Co-authors:
andrewmathias8
Rationale for change
Added hint
It can be answered as "alpha 1" only.
Tamsulosin is used specifically for BPH because it has selective effect on alpha 1A, and almost no effect on alpha 1B (1B are present in blood vessels responcible for the hypotensive effect)
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α1A receptor: prostate
α1B receptor: blood vessels
Terazosin: selective for α1 and non-selective for subtypes (α1A-D)
Tamsulosin: selective for α1 and selective for subtypes α1A and α1D (no α1B antagonism therefore does not affect blood pressure)
α1B receptor: blood vessels
Terazosin: selective for α1 and non-selective for subtypes (α1A-D)
Tamsulosin: selective for α1 and selective for subtypes α1A and α1D (no α1B antagonism therefore does not affect blood pressure)
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Bootcamp
Watch associated Bootcamp video - Male Pathology : Benign Prostatic Hyperplasia
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Watch associated Bootcamp video - Pharmacology : Tamsulosin, Minoxidil, Tocolytics
Watch associated Bootcamp video - Urinary Incontinence : Micturition Overview
Watch associated Bootcamp video - Autonomic System : Alpha Adrenergic Antagonists
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