Accepted
at 11:33 p.m. Oct, 25, 2025
by
andrewmathias8
Author:
andrewmathias8
Type of change:
Updated content
Rationale for change
Nigro is chemoradiation. Also per its dupe
Source: AMBOSS - https://next.amboss.com/us/article/gS0F_2?q=%22nigro%20chemoradiation%22#Y56007e1b1ba9e8c93c459f176b5ddb66
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- Surgery only if residual tumor or anal margin cancer
- Squamous cell carcinoma of the anus is more common in HIV-positive individuals and men who have receptive sex with men
- Symptoms include a fungating mass growing out of the anus and often, metastatic inguinal nodes
- Diagnosis is made through biopsy
- Treatment involves the Nigro chemoradiation protocol, followed by surgery if there is residual tumor
- The 5-week chemo-radiation protocol has a 90% success rate, making surgery rarely necessary
- Squamous cell carcinoma of the anus is more common in HIV-positive individuals and men who have receptive sex with men
- Symptoms include a fungating mass growing out of the anus and often, metastatic inguinal nodes
- Diagnosis is made through biopsy
- Treatment involves the Nigro chemoradiation protocol, followed by surgery if there is residual tumor
- The 5-week chemo-radiation protocol has a 90% success rate, making surgery rarely necessary
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
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Sketchy
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Sketchy 2
Extra section:
Watch Anorectal Cancer
Extra section:
Watch Anorectal Cancer
Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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Bootcamp
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OME
Additional Resources
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