Created at 8:20 p.m. Sep, 21, 2025
Author:
adavis98
Rationale for change
More specific question. Warfarin in contraindicated in pregnancy. On wards, you will often see women with APLS with h/o recurrent pregnant loss who are either pregnant or trying to get pregnant, and thus we treat them with LMWH.
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- Primary thromboprophylaxis (meaning no active or recent thrombus when treatment is initiated) approach is low-dose aspirin (controversial)
Secondary thromboprophylaxis (period 3–6 months after treating acute thrombosis):
- First-line = warfarin
- Second-line = LMWH or UFH
- Pregnant patients = low-dose aspirin + heparin (LMWH or UFH)
Secondary thromboprophylaxis (period 3–6 months after treating acute thrombosis):
- First-line = warfarin
- Second-line = LMWH or UFH
- Pregnant patients = low-dose aspirin + heparin (LMWH or UFH)
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