Created at 11:38 a.m. Sep, 07, 2025
Author:
lmoffer
Type of change:
Updated content
Rationale for change
Hey, I'm not positive, but is the cloze answer of dihydropteridine reductase supposed to be the same enzyme shown in the photo reducing BH2 to BH4 as written: dihydrobiopterin reductase. Maybe it's two different names for the same enzyme or maybe they're different enzymes? I just wanted to submit this in case one of them happens to be written incorrectly. Thanks!
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- Which causes a tetrahydrobiopterin (BH4) deficiency
- Lack of dihydropteridine reductase prevents reduction of BH2 back to BH4 using NADH; patients can also have a deficiency of BH4 itself
- May present with symptoms of decreased neurotransmitter levels (e.g., hyperprolactinemia due to loss of dopamine inhibition)

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Sketchy



Watch Biochemistry Inborn Errors of Amino Acid Metabolism & Phenylketonuria (PKU)
Watch Pediatric Inborn Errors of Amino Acid Metabolism & Phenylketonuria (PKU)



Watch Biochemistry Inborn Errors of Amino Acid Metabolism & Phenylketonuria (PKU)
Watch Pediatric Inborn Errors of Amino Acid Metabolism & Phenylketonuria (PKU)
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Watch associated Bootcamp video - Protein Metabolism : Phenylalanine, Tyrosine, and Catecholamines
Watch associated Bootcamp video - Protein Metabolism : Clinical Implications of Phenylalanine Metabolism: Phenylketonuria
Watch associated Bootcamp video - Protein Metabolism : Clinical Implications of Phenylalanine Metabolism: Phenylketonuria
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