Created at 1:59 p.m. Sep, 03, 2025
Author: WesleyWyatt
Related Note: 1482886567135 2
Rationale for change

AMBOSS, FA2024/2025, and all of the MEDIA INCLUDED IN THIS CARD agree that Hirschsprung disease is a failure of neural crest cells to migrate, not ganglion cells.

If the neural crest cells fail to migrate, then they cannot form ganglia. Ganglia are the plexuses the descending cells will mature into.

Additional sources:

https://pubmed.ncbi.nlm.nih.gov/23528997/

https://pubmed.ncbi.nlm.nih.gov/36417785/

https://pubmed.ncbi.nlm.nih.gov/35690468/
Source: AMBOSS - https://next.amboss.com/us/article/q40C4T?q=hirschsprung+disease

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