Created at 1:15 p.m. Aug, 16, 2025
Author:
ronin16319
Type of change:
Content error
Rationale for change
The way the card is currently written implies that the dihydropyridine receptor uses Ca2+ as its ligand. It is a Ca2+ channel, not a Ca2+ receptor.
This change has been suggested before, but was rejected due to insufficient referencing.
AMBOSS: Muscle tissue > Excitation-contraction coupling > Dihydropyridine receptor (pop up)
https://next.amboss.com/us/article/so0tWS
"Dihydropyridine receptor
Abbreviation: DHPR
An L-type, voltage-gated calcium channel found in the T-tubules of skeletal muscle. Responds to voltage changes (e.g., from muscle cell depolarization) and facilitates the release of intracellular calcium stored in the sarcoplasmic reticulum, which leads to skeletal muscle contraction."
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The T-tubule is important for allowing depolarization to rapidly propagate through the interior of the muscle fiber, ensuring synchronized calcium release and contraction of myofibrils
Lecture Notes
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Watch Skeletal Muscle Fibers



Watch Excitation-Contraction Coupling in Skeletal Muscle






Watch Skeletal Muscle Fibers



Watch Excitation-Contraction Coupling in Skeletal Muscle
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Review Dihydropyridines


Review Dihydropyridines
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Bootcamp
Watch associated Bootcamp video - Skeletal Muscle Depolarization
Watch associated Bootcamp video - Muscle Contraction and Relaxation
Watch associated Bootcamp video - Vasodilation and Vasoconstriction: Excitation-Contraction Coupling
Watch associated Bootcamp video - Skeletal Muscle: Skeletal Muscle - Overview
Watch associated Bootcamp video - Muscle Contraction and Relaxation
Watch associated Bootcamp video - Vasodilation and Vasoconstriction: Excitation-Contraction Coupling
Watch associated Bootcamp video - Skeletal Muscle: Skeletal Muscle - Overview
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