Rejected
at 4:26 p.m. Dec, 29, 2025 ]
by
Ahmed7
Author:
henryzou
Type of change:
Updated content
Rationale for change
Treatment for polycythemia vera:
First-line: {{c1::phlebotomy}}
Second-line: {{c1::hydroxyurea}}
Third-line: {{c1::ruxolitinib}}
Source: Society Guidelines - https://www.nejm.org/doi/full/10.1056/NEJMoa1409002
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Treatment for polycythemia vera:
First-line: {{c1::phlebotomy}}
Second-line: {{c1::hydroxyurea}}
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid


hydroxyurea: block ribonucleotide reductase decreasing dUDP = decrease DNA precursors = less cellular proliferation


Sketchy



Watch Methotrexate, Leucovorin, 5-fluorouracil, Hydroxyurea



Watch Myeloproliferative Neoplasms & Myelodysplastic Syndromes


Watch Polycythemia



Watch Methotrexate, Leucovorin, 5-fluorouracil, Hydroxyurea



Watch Myeloproliferative Neoplasms & Myelodysplastic Syndromes


Sketchy 2
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Picmonic
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Pixorize
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Physeo
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Bootcamp
Watch associated Bootcamp video - Plasma Cell Dyscrasias and Myeloproliferative Disease: Polycythemia Vera and Essential Thrombocythemia
Watch associated Bootcamp video - DNA Structure : Clinical Applications of the Pyrimidine Pathway
Watch associated Bootcamp video - DNA Structure : Clinical Applications of the Pyrimidine Pathway
OME
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