Created at 10:27 a.m. Jul, 08, 2025
Author:
mohannadkh10
Type of change:
Updated content
Rationale for change
The question describes a suicidal patient with multiple attempts who does not meet criteria for MDD and asks for the expected finding. The correct answer is low concentration of 5-hydroxyindoleacetic acid in the cerebrospinal fluid.
This association is also mentioned in UW Step 1 question 8878, in the explanation of a wrong option:
Low CSF 5-hydroxyindoleacetic acid, a metabolite of serotonin, has been associated with impulsive, destructive behaviors, particularly aggression, suicide, and violence
Source: UWorld - Step 2 15897
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