Accepted at 2:50 a.m. Nov, 01, 2023 by dollajas
Author: CorellianSmuggler
Co-authors: dollajas
Related Note: 1482359666657
Rationale for change

Amboss states this deficiency is caused by a mutated gene. A protein makes sense, but for completeness, updated to add "gene" to the end of the card.
Source: AMBOSS - https://next.amboss.com/us/article/4o03XS?q=microsomal+triglyceride+transfer+protein#Z3672efc521c2f52d9b9beddbaa38f4b8

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Extra
- Defect in the MTP gene; MTTP functions as a chaperone protein necessary for proper folding of apoB and helps transfer lipids to newly formed chylomicrons

- Normally, chylomicrons and VLDL particles are synthesized within the ER as lipids accumulate around a single apo B
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Watch associated Bootcamp video - Lipid Metabolism : Lipid Digestion and Absorption: Cholesterol and Clinical Implications
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