Created at 5:31 p.m. Jul, 04, 2025
Author:
arh767
Type of change:
Updated content
Rationale for change
This could also be hemoglobinuria
Source: UWorld - Step 1 20158
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- The "blood" is myoglobin
- Etiology: direct muscle damage, drugs (statins, fibrates, colchicine, cocaine)
- Labs: ↑ CK, ↑ K+, ↑ myoglobin → ATN → renal failure, dipstick positive for blood but not RBCs
- Treatment: aggressive hydration, identify and treat the underlying cause, mannitol*, urine alkalinization*

Photo credit: James Heilman, MD, CC BY-SA 3.0, via Wikimedia Commons
- Etiology: direct muscle damage, drugs (statins, fibrates, colchicine, cocaine)
- Labs: ↑ CK, ↑ K+, ↑ myoglobin → ATN → renal failure, dipstick positive for blood but not RBCs
- Treatment: aggressive hydration, identify and treat the underlying cause, mannitol*, urine alkalinization*

Photo credit: James Heilman, MD, CC BY-SA 3.0, via Wikimedia Commons
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