Rejected at 3:28 a.m. Nov, 27, 2025 ] by andrewmathias8
Author: kaguilarhms
Co-authors: andrewmathias8
Related Note: 1556737837096
Rationale for change

CA-125 is a tumor marker elevated in the following:
Ovarian carcinoma
Other gynecologic malignancies
Malignant ascites
Certain lymphomas
Cholangiocarcinoma

I believe you meant to put CA-125 elevation w. the malignancy scenario. There are reports of elevated CA-125 in tubo-ovarian abcess (https://pubmed.ncbi.nlm.nih.gov/8150372/#:~:text=mimicking%20ovarian%20carcinoma-,Highly%20elevated%20CA125%20and%20tubo%2Dovarian%20abscess%20mimicking%20ovarian%20carcinoma,doi:%2010.1159/000292544.) but this is more rare.
Source: AMBOSS - https://next.amboss.com/us/article/ol00BT?utm_source=navbar&utm_medium=anki&utm_campaign=anki&utm_term=ca%2B125&guid=zswcs%257D%253Avk5&aid=e37114ea-1137-40c7-95fc-37e8537d880b&uid=HzmhK8ReY#Z3cf4f38d85d743385432afe95e3e2cc5

Rejection reason

CA-125 can be a nonspecific finding, it's meant to be there as a distractor. Perhaps this needs clarification in Extra (please feel free to submit a suggestion!). See the discussion in the link below regarding previous decisions to not make this change:

https://community.ankihub.net/t/07-09-2024-updated-content-anking-step-deck-ankingmed-id-1833321/255989?u=andrewmathias8

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