Accepted
at 11:05 p.m. Apr, 28, 2025
by
IantheBFG
Author:
IantheBFG
Co-authors:
andrewmathias8
Type of change:
Updated content
Rationale for change
Additional details to extra on WHY these treatments are used to help remember pathophys and mechanism
SOURCE AMBOSS #AMBOSS::3G0S_h
"In patients with Goodpasture syndrome, emergent plasmapheresis is used to eliminate antibodies that are directed at the basement membrane of alveoli and glomeruli (anti-GBM). Immunosuppressive treatment with prednisone and cyclophosphamide is commonly performed in combination with plasmapheresis to reduce new antibody formation. Without proper treatment, Goodpasture syndrome rapidly progresses to end-stage renal disease. However, if therapy is initiated early, full recovery of renal function may be reached in > 50% of cases."
Source: AMBOSS - #AMBOSS::3G0S_h
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