Accepted at 4:35 a.m. Oct, 02, 2025 by Ahmed7
Author: roseee
Co-authors: Ahmed7 , mohannadkh10 , andrewmathias8 , gnigam
Related Note: 1523051363552 2
Rationale for change

on NBME form 13, section 3, question 42

A vignette of a woman using laxatives daily for purging

Question: which lab findings are most likely to be found in this patient?

Answer: a set of findings with metabolic ACIDosis.

Explanation: "In this patient with chronic laxative abuse, metabolic alkalosis is possible because of a proposed mechanism involving hypovolemia and aldosterone synthesis leading to renal exchange of bicarbonate. However, in laxative overuse, the loss of bicarbonate in the stool would likely promote a metabolic acidosis with certainty."

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