Accepted
at 12:37 a.m. Oct, 07, 2025
by
Jwill
Author:
Jwill
Co-authors:
andrewmathias8
Type of change:
Updated content
Rationale for change
NBME CCSSA 10
67 yo pt: has radiating pain and asks most appropriate pharmacotherapy
answer: add oral nortriptyline at bedtime
We do have nid:1485042614659 that points out that secondary amines "have the least anticholinergic effects"
But I think this addition to this card helps to emphasize that these may still be seen in the elderly population
AMBOSS supports
Source: AMBOSS - https://next.amboss.com/us/article/_N05dg?q=Tricyclic%20antidepressants#IncYu10
Before
After
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TCAs are relatively contraindicated in {{c1::elderly}} patients due to severe anticholinergic and antihistamine effects
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid


Sketchy



Watch Tricyclic Antidepressants



Sketchy 2
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Sketchy Extra
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Picmonic
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Pixorize




Physeo
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Bootcamp
Watch associated Bootcamp video - Pharmacology: Tricyclic Antidepressants
Watch associated Bootcamp video - Side Effects and Toxins: Age Considerations for Pharmacokinetics
Watch associated Bootcamp video - Side Effects and Toxins: Age Considerations for Pharmacokinetics
OME
Additional Resources
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