Accepted at 5:54 p.m. Apr, 19, 2025 by Ahmed7
Author: docox123
Related Note: 1553851782503
Rationale for change

added nbme12 tag b/c directly helps answer the Q:

A 30-year-old man who is in the US Army is brought to the emergency department of a military hospital 40 minutes after being hit by a motor vehicle traveling 25 mph while he was walking. On arrival, he is
unconscious. Temperature is 36.0°C (96.8°F), pulse is 113/min, respirations are 22/min, and blood pressure
is 80/55 mm Hg. Pulse oximetry on room air shows an oxygen saturation of 90%. On examination, the
abdomen is rigid. He is resuscitated with 8 units of packed red blood cells, 6 units of fresh frozen plasma,
and 2 units of platelets. Emergency laparotomy shows transection of the small bowel 5 cm proximal to the
cecum. Laboratory studies done 45 minutes after arriving in the surgical intensive care unit show an
activated partial thromboplastin time of 42 seconds and a prothrombin time of 25 seconds (INR=3.2). Which of the following is the most likely cause of the coagulation abnormalities in this patient?

Ans: DIC

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#AK_Step2_v12::#NBME::Form12
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