Rejected
at 10:21 p.m. Apr, 03, 2025 ]
by
pkaps01
Author:
wdmccomb
Type of change:
Updated content
Rationale for change
No such thing as negative sense DNA
Rejection reason
Updated this card to address concerns. Please see linked discussion in comments.
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The noncoding (antisense/template) strand is the DNA strand that is read by RNA Polymerase II to create mRNA. Therefore, the sequence of the noncoding strand in the 5' to 3' direction is complementary to the mRNA transcript read in the 3' to 5' direction (swapping U for T). 
The coding (sense) strand is the DNA strand that complements the noncoding DNA strand and therefore has the same sequence and directionality as the newly synthesized mRNA (have to switch T with U, though).
The noncoding (antisense/template) strand is the DNA strand that is read by RNA Polymerase II to create mRNA. Therefore, the sequence of the noncoding strand in the 5' to 3' direction is complementary to the mRNA transcript read in the 3' to 5' direction (swapping U for T).
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