Created at 4:50 p.m. Apr, 02, 2025
Author: eren.sakarcan
Related Note: 1517169728142 1
Rationale for change

Uworld says dexamethasone pre-treatment isn't effective in gram-negative (h. influenzae, n. meningitidis) bacterial meningitis bc gram-negative cell wall is thinner and lacks teichoic acid/pro-inflammatory triggers = less intense cytokine response = less inflammatory reaction in CSF; only helpful for gram-positive meningitis (s. pneumo)
Source: UWorld - Step 1 14899

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#AK_Step2_v12::!Shelf::#Cards_AnKing_Did::3peds #AK_Step1_v12::#Bootcamp::Microbiology::33_Infectious_Neuropathology::06_Management_of_Meningoencephalitis #AK_Step2_v12::#OME_banner #AK_Step2_v12::#Subjects::Microbiology::01_Bacteria::06_Gram_Negative_Bacilli_Respiratory::Haemophilus_Influenza::Meningitis #AK_Step2_v12::#SketchyPeds::09_Infectious_Diseases::02_Neurologic_&_Eye_Infections::02_Meningitis_in_Children_>1_mo #AK_Other::#AK_Original_Decks::Step_2::Cheesy_Dorian_(M3) #AK_Step2_v12::#FirstAid::09_Neuro::09_CNS_Infections::01_Meningitis #AK_Step2_v12::#AMBOSS::Xo090S #AK_Step1_v12::#Bootcamp::Microbiology::05_Streptococcus::01_Streptococcus_Pneumoniae #AK_Step2_v12::!Shelf::Peds::no_dupes::only_step2 #AK_Step2_v12::Original_decks::Zanki_Step_2::Peds::ID #AK_Step2_v12::Original_decks::Dorian::peds::uw::peds_id #AK_Step2_v12::#Resources_by_rotation::Peds::uworld::pediatric_infectious_disease::pediatric_infectious_disease_zanki #AK_Step1_v12::#UWorld::Step::14899 #AK_Step1_v12::#UWorld::COMLEX::26002 #AK_Step2_v12::#UWorld::Step::2442 #AK_Step2_v12::#AMBOSS::Wi0Pqf #AK_Step2_v12::#B&B::08_Infectious_Disease::04_Other::03_Meningitis::Extra #AK_Step2_v12::#Bootcamp::Pediatrics::03_Infectious_Disease::01_Otologic_Infections::06_Pediatric_Meningoencephalitis #AK_Step2_v12::#Resources_by_rotation::Peds::uworld::pediatric_infectious_disease::peds_infectious_disease_dorian #AK_Step2_v12::#Subjects::Neurology::01_Ear::Hearing_Loss #AK_Step2_v12::#Subjects::Microbiology::01_Bacteria::06_Gram_Negative_Bacilli_Respiratory::Haemophilus_Influenza #AK_Other::Only_Step_2 #PANCE::EOR::PEDS