Accepted
at 4:15 a.m. Mar, 04, 2025
by
Ahmed7
Author:
docox123
Rationale for change
added tag for NBME form 10, b/c the answer to the question is directly related to this card, I couldn't fit the whole question in this description b/c it was too long, but I've attached the educational objective:
Educational Objective: Felty syndrome should be suspected in patients with longstanding, poorly controlled, seropositive RA with new-onset splenomegaly and neutropenia. A peripheral smear should be evaluated to exclude LGL leukemia. Rituximab, a monoclonal antibody targeting CD20 expressed on the surface of B lymphocytes, is the treatment of choice.
No changes in fields
Text
{{c1::Felty}} syndrome is {{c3::rheumatoid arthritis}} with {{c2::neutropenia}} and {{c2::splenomegaly}}
Extra
- Often presents with recurrent bacterial infection (due to neutropenia)
- May also present with lower extremity skin ulceration
- Symptoms generally improve with treatment of the underlying RA
- Patients are frequently positive for HLA-DR4
- May also present with lower extremity skin ulceration
- Symptoms generally improve with treatment of the underlying RA
- Patients are frequently positive for HLA-DR4
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
Sketchy
Sketchy 2
Sketchy Extra
Watch Rheumatoid Arthritis
Watch Rheumatoid Arthritis
Picmonic
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Pixorize
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Physeo
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OME
Additional Resources
Atlas:
Atlas:
One by one
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