Created at 11:47 p.m. Feb, 23, 2025
Author: WesleyWyatt
Related Note: 1479351731008 3
Rationale for change

Chromaffin cells are the cells that make up the matured adrenal medulla, but prior to maturation, the cells that migrate and form the adrenal medulla are neural crest cells/SCP's (a specific neural crest derivative that is not of importance other than it not being a matured chromaffin cell). This is also why a neuroblastoma is made of neural crest cells, not chromaffin cells. The migrating cells have not yet matured, making Cloze 2 incorrect. The wording in Cloze 2 is also unsupported by any other common resources like FA/UWorld, etc.

Two papers which thoroughly document the migration and maturation of neural crest cells traveling to the adrenal medulla are below.

Required info in the abstract: https://pmc-ncbi-nlm-nih-gov.proxy.mul.missouri.edu/articles/PMC6013038/

More lengthy: https://pmc-ncbi-nlm-nih-gov.proxy.mul.missouri.edu/articles/PMC6240312/

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